1453095-80-1Relevant academic research and scientific papers
Electrophile-driven copper-catalyzed one-pot synthesis of 3-halogen quinoline derivatives
Cheng, Jie,Zhai, Hong,Bai, Jun,Tang, Jun,Lv, Ling,Sun, Bei
, p. 4044 - 4046 (2015/02/02)
A convenient and regioselective one-pot synthesis of 3-chloride or 3-bromide quinoline derivatives was achieved through a Grignard addition reaction by alkynyl Grignard regent to o-trifluoroacetyl aniline and a Cu(II)-catalyzed cyclization-halogenation tandem reaction with aqueous HCl or HBr as electrophilic reagent.
Electrophile-driven copper-catalyzed one-pot synthesis of 3-halogen quinoline derivatives
Cheng, Jie,Zhai, Hong,Bai, Jun,Tang, Jun,Lv, Ling,Sun, Bei
supporting information, p. 4044 - 4046 (2014/07/22)
A convenient and regioselective one-pot synthesis of 3-chloride or 3-bromide quinoline derivatives was achieved through a Grignard addition reaction by alkynyl Grignard regent to o-trifluoroacetyl aniline and a Cu(II)-catalyzed cyclization-halogenation tandem reaction with aqueous HCl or HBr as electrophilic reagent.
