145315-01-1Relevant articles and documents
Organoboranes for synthesis. 13. Simple, efficient syntheses of long-chain alcohols and carboxylic acids
Brown, Herbert C.,Iyer, Ramakrishnan R.,Bhat, Narayan G.,Racherla, Uday S.,Brown, Charles A.
, p. 9187 - 9194 (1992)
General, convenient and simple syntheses of long straight chain alcohols and carboxylic acids were developed utilizing organoborane chemistry. One of the methods entails the thermal isomerization of long-chain alkyldicyclohexylboranes, followed by oxidation. An alternative procedure for the preparation of long-chain alcohols involves the KAPA isomerization of internal alkynes to the terminal derivative, followed by dihydroboration with 9-BBN and oxidation. Alternatively, the terminal alkyne can be oxidised directly to the carboxylic acid. In another strategy, the C30-alcohol triaxontanol was prepared by employing high pressure carbonylation of a borane intermediate.
