1453196-50-3Relevant academic research and scientific papers
Highly enantioselective intermolecular hydroamination of allylic amines with chiral aldehydes as tethering catalysts
MacDonald, Melissa J.,Hesp, Colin R.,Schipper, Derek J.,Pesant, Marc,Beauchemin, André M.
, p. 2597 - 2601 (2013/03/14)
Chirally LinkedIn: Chiral aldehydes are effective tethering catalysts for enantioselective intermolecular hydroamination, which provides access to vicinal diamine motifs in good yields and excellent enantioselectivities (see scheme). This work highlights simple chiral α-oxygenated aldehydes as effective organocatalysts capable of efficiently inducing asymmetry through transient intramolecularity. Copyright
