1453196-72-9Relevant academic research and scientific papers
Highly enantioselective intermolecular hydroamination of allylic amines with chiral aldehydes as tethering catalysts
MacDonald, Melissa J.,Hesp, Colin R.,Schipper, Derek J.,Pesant, Marc,Beauchemin, André M.
supporting information, p. 2597 - 2601 (2013/03/14)
Chirally LinkedIn: Chiral aldehydes are effective tethering catalysts for enantioselective intermolecular hydroamination, which provides access to vicinal diamine motifs in good yields and excellent enantioselectivities (see scheme). This work highlights simple chiral α-oxygenated aldehydes as effective organocatalysts capable of efficiently inducing asymmetry through transient intramolecularity. Copyright
