1453211-59-0

Basic information

• Product Name: 2-chloro-5-[1-(3,5-dimethoxyphenyl)ethoxy]pyrimidine
• Synonyms: 2-chloro-5-[1-(3,5-dimethoxyphenyl)ethoxy]pyrimidine
• CAS NO: 1453211-59-0
• Molecular Weight: 294.738
• Mol File: 1453211-59-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-5-[1-(3,5-dimethoxyphenyl)ethoxy]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-5-[1-(3,5-dimethoxyphenyl)ethoxy]pyrimidine(1453211-59-0)
• EPA Substance Registry System: 2-chloro-5-[1-(3,5-dimethoxyphenyl)ethoxy]pyrimidine(1453211-59-0)

Safety Data

• Hazardous Substances Data: 1453211-59-0(Hazardous Substances Data)

Upstream product

• 14950-55-1 rac-1-(3,5-dimethoxyphenyl)ethan-1-ol 
• 4983-28-2 2-chloropyrimidine-5-ol 

Relevant articles and documents

NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND

Provided is a compound useful as a prophylactic and/or therapeutic agent for bladder cancer. As a result of studies on compounds having FGFR inhibitory action, the present inventors have found that the nitrogen-containing aromatic heterocyclic compounds of the present invention have inhibitory action on FGFR1, FGFR2, and/or FGFR3, particularly, mutant FGFR3, and thus, the present invention has been accomplished. The nitrogen-containing aromatic heterocyclic compound of the present invention can be used as a therapeutic agent for various cancers related to FGFR1, FGFR2, and/or FGFR3, such as lung cancer and hormone therapy-resistant breast cancer, stomach cancer, triple negative breast cancer, endometrial cancer, bladder cancer, and glioblastoma, particularly as a prophylactic and/or therapeutic agent for mutant FGFR3-positive bladder cancer.