1453215-83-2Relevant academic research and scientific papers
Unusual Reactions of the 1,3-Dithiane Derivative of the Garner Aldehyde and Related Compounds
Philip, Anijamol T.,Chacko, Shibin,Ramapanicker, Ramesh
, p. 1997 - 2002 (2013)
Treatment of the 1,3-dithiane derivative of the Garner aldehyde with alkyl halides in the presence of n-butyllithium resulted in a ring-opening reaction to give differentially substituted propane-1,3-dithioethers, instead of the expected 2,2-dialkylated 1,3-dithiane products. The corresponding 1,3-dithiolane derivative also reacted in a similar manner. Such ring-opening reactions of dithiane or dithiolane derivatives are rare. A detailed study of this unusual reaction was carried out and a possible mechanism is proposed. Georg Thieme Verlag Stuttgart, New York.
