1453490-52-2Relevant academic research and scientific papers
Phosphorus(V)-catalyzed deoxydichlorination reactions of aldehydes
An, Jie,Tang, Xiaoping,Moore, Joshua,Lewis, William,Denton, Ross M.
, p. 8769 - 8776 (2013)
A phosphine oxide-catalyzed conversion of aldehydes into 1,1-dichlorides is reported. The reaction proceeds via a phosphorus(V)-catalysis manifold in which phosphine oxide turnover is achieved using oxalyl chloride as a consumable reagent. The new method is applicable to a range of aldehydes and, in combination with palladium-catalyzed reductive dimerization, gives rise to a new catalytic approach to the synthesis of stilbenes and a short formal synthesis of resveratrol.
