145356-32-7

Basic information

• Product Name: 4-Hydroxy Xylazine
• Synonyms: 4-Hydroxy Xylazine;4-[(5,6-Dihydro-4H-1,3-thiazin-2-yl)aMino]-3,5-diMethylphenol
• CAS NO: 145356-32-7
• Molecular Formula: C12H16N2OS
• Molecular Weight: 236.33324
• Product Categories: Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Sulfur & Selenium Compounds;Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 145356-32-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 250-252°C (dec.)
• Boiling Point: 391.684°C at 760 mmHg
• Flash Point: 190.684°C
• Appearance: /
• Density: 1.255g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.632
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 10.85±0.36(Predicted)
• CAS DataBase Reference: 4-Hydroxy Xylazine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydroxy Xylazine(145356-32-7)
• EPA Substance Registry System: 4-Hydroxy Xylazine(145356-32-7)

Safety Data

• Hazardous Substances Data: 145356-32-7(Hazardous Substances Data)

Usage

Description

4-Hydroxy Xylazine, also known as a major metabolite of Xylazine, is a compound derived from the metabolism of Xylazine (Item Nos. 14113 | 22641). Xylazine is an agonist of α2-adrenergic receptors, which is utilized for sedation, anesthesia, and analgesia in non-human mammals. The chemical properties of 4-Hydroxy Xylazine are characterized as an off-white to tan solid.

Uses

Used in Pharmaceutical Industry:
4-Hydroxy Xylazine is used as a metabolite marker for detecting xylazine doping in the pharmaceutical industry. It is particularly useful in mass spectrometry (MS) analysis of equine urine, helping to identify the use of Xylazine in horses for non-therapeutic purposes.
Used in Research and Development:
In the field of research and development, 4-Hydroxy Xylazine serves as a valuable compound for studying the metabolism and pharmacokinetics of Xylazine. This understanding can contribute to the development of improved sedative, anesthetic, and analgesic agents for veterinary medicine.
Used in Quality Control and Regulatory Compliance:
4-Hydroxy Xylazine is used as a reference substance in quality control and regulatory compliance for the pharmaceutical industry. It helps ensure the safety and efficacy of Xylazine-based products by providing a standard for comparison and validation of analytical methods.
Used in Toxicology and Forensic Analysis:
In toxicology and forensic analysis, 4-Hydroxy Xylazine plays a role as a biomarker for the detection and quantification of Xylazine exposure. This is particularly relevant in cases where the misuse or abuse of Xylazine in animals may be under investigation.

InChI:InChI=1/C12H16N2OS/c1-8-6-10(15)7-9(2)11(8)14-12-13-4-3-5-16-12/h6-7,15H,3-5H2,1-2H3,(H,13,14)