145372-34-5 Usage
Uses
Used in Pharmaceutical Industry:
2,3,3a,6,7,7a-Hexahydro-5',7a-diMethyl-4-hydroxy-indene-(1R)-1'-pentanoic Acid Methyl Ester 4-O-TrifluoroMethanesulfonate is used as an intermediate in the preparation of Dihydroxyvitamin D3 and associated metabolites. Its role in the synthesis of these essential compounds highlights its importance in the development of treatments for various health conditions related to vitamin D deficiency or imbalance.
Used in Chemical Synthesis:
As a light yellow oil, 2,3,3a,6,7,7a-Hexahydro-5',7a-diMethyl-4-hydroxy-indene-(1R)-1'-pentanoic Acid Methyl Ester 4-O-TrifluoroMethanesulfonate can be utilized in various chemical synthesis processes. Its specific functional groups and structural features make it a valuable building block for creating a range of other organic compounds, potentially leading to new materials or pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 145372-34-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,3,7 and 2 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 145372-34:
(8*1)+(7*4)+(6*5)+(5*3)+(4*7)+(3*2)+(2*3)+(1*4)=125
125 % 10 = 5
So 145372-34-5 is a valid CAS Registry Number.
145372-34-5Relevant academic research and scientific papers
Ultrasonically Induced Conjugate Addition of Iodides to Electron-Deficient Olefins and Its Application to the Synthesis of Side-Chain Analogs of the Hormone 1α,25-Dihydroxyvitamin D3
Sestelo, Jose Perez,Mascarenas, Jose L.,Castedo, Luis,Murino, Antonio
, p. 118 - 123 (2007/10/02)
A versatile method for the rapid construction of fragments related to the upper part of vitamin D3 from the Lythgoe-Inhoffen diol is described.The key feature of the strategy is a new zinc-copper-induced conjugate addition of iodo triflate 10a to electron-deficient olefins under sonochemical aqueous conditions.These fragments are rapidly and efficiently transformed via the dienyne convergent approach to several derivatives of the hormone 1α,25-(OH)2-D3 modified at C-25.
