145383-45-5

Upstream product

• 82462-50-8 2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid 
• 127676-66-8 C₂₀H₁₇NO₅ 
• 145416-96-2 1,3,5-tri-O-benzoyl-2-deoxy-D-ribofuranose 

Relevant academic research and scientific papers

A Facile Preparative Method of C-Nucleosides

Facile and general preparative method of C-nucleosides has been achieved via 4 steps starting from 2-deoxy-D-ribose.The essential step in this method is the use of radical coupling reaction of 2-deoxy-D-ribofuranosyl radical derivative and some heteroaromatic bases.

Synthesis of C-Nucleosides via Radical Coupling Reaction

Photolysis of O-acyl derivatives of N-hydroxy-2-thiopyridone, prepared from tetrahydrofuran-2-carboxylic acid, D-ribofuranosylmethanoic acid, and D-ribopyranosylmethanoic acid, gave the corresponding C-nucleoside derivatives in the presence of heteroaromatic compounds via radical pathways.The essential step in this method is a radical coupling reaction of D-ribofuranosyl radical or D-ribopyranosyl radical and some heteroaromatic bases.This is a new method for the preparation of C-nucleosides using sugar carboxylic acids.