1453835-19-2

Upstream product

• 1453186-96-3 4-chloro-2-(methylsulfanyl)-8-(propan-2-yl)pyrazolo[1,5-a][1,3,5]triazine 
• 1453186-95-2 8-isopropyl-2-(methylsulfanyl)pyrazolo[1,5-a][1,3,5]triazin-4(3H)-one 
• 1453186-94-1 8-isopropyl-2-thioxo-2,3-dihydropyrazolo[1,5-a][1,3,5]triazin-4(1H)-one 
• 1453835-22-7 N-(2-(1H-pyrazol-1-yl)benzyl)-8-isopropyl-2-(methylsulfonyl)pyrazolo[1,5-a][1,3,5]triazin-4-amine 
• 151521-49-2 4-isopropyl-1 H-pyrazol-5-amine 
• 1453837-36-9 N-(2-(1H-pyrazol-1-yl)benzyl)-8-isopropyl-2-(methylthio)-pyrazolo[1,5-a][1,3,5]triazin-4-amine 

Downstream Products

• 1453835-20-5 N-(2-(1H-pyrazol-1-yl)benzyl)-2-bromo-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-4-amine 
• 1453835-21-6 tert-butyl (2-(1H-pyrazol-1-yl)benzyl-2-bromo-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-4-yl)carbamate 
• 1453835-16-9 N-(2-(1H-pyrazol-1-yl)benzyl)-8-isopropyl-2-(piperidin-3-ylmethyl)pyrazolo[1,5-a][1,3,5]triazin-4-amine 

Relevant academic research and scientific papers

PYRAZOLO-TRIAZINE AND/OR PYRAZOLO-PYRIMIDINE DERIVATIVES AS SELECTIVE INHIBITOR OF CYCLIN DEPENDENT KINASE

The present invention relates to pyrazolo[1,5-a][1,3,5]triazine and pyrazolo[l,5-a]pyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of cell proliferative diseases, inflammatory diseases, immunological diseases, cardiovascular diseases and infectious diseases. Furthermore, the present invention is directed towards pharmaceutical compositions containing at least one of the pyrazolo[1,5-a][1,3,5]triazine and pyrazolo[1,5-a]pyrimidine derivatives and/or pharmaceutically acceptable salts thereof.

PYRAZOLO - TRIAZINE DERIVATIVES AS SELECTIVE CYCLIN- DEPENDENT KINASE INHINITORS

The present invention relates to pyrazolo[1,5-a][1,3,5]triazine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, immunological diseases, autoimmune diseases, cardiovascular diseases, cell proliferative diseases, inflammation, erectile dysfunction and stroke, and pharmaceutical compositions containing at least one of said pyrazolo[1,5-a][1,3,5]triazine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said pyrazolo[1,5-a][1,3,5]triazine derivatives as inhibitors for a protein kinase.