1453854-02-8

Basic information

• Product Name: (R)-tert-butyl 3-((R)-(4-chloro-3-fluorophenyl)(4-(2-(methylthio)pyrimidin-4-yl)-2-oxopyridin-1(2H)-yl)methyl)pyrrolidine-1-carboxylate
• Synonyms: (R)-tert-butyl 3-((R)-(4-chloro-3-fluorophenyl)(4-(2-(methylthio)pyrimidin-4-yl)-2-oxopyridin-1(2H)-yl)methyl)pyrrolidine-1-carboxylate
• CAS NO: 1453854-02-8
• Molecular Weight: 531.051
• Mol File: 1453854-02-8.mol

Chemical Properties

• CAS DataBase Reference: (R)-tert-butyl 3-((R)-(4-chloro-3-fluorophenyl)(4-(2-(methylthio)pyrimidin-4-yl)-2-oxopyridin-1(2H)-yl)methyl)pyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-tert-butyl 3-((R)-(4-chloro-3-fluorophenyl)(4-(2-(methylthio)pyrimidin-4-yl)-2-oxopyridin-1(2H)-yl)methyl)pyrrolidine-1-carboxylate(1453854-02-8)
• EPA Substance Registry System: (R)-tert-butyl 3-((R)-(4-chloro-3-fluorophenyl)(4-(2-(methylthio)pyrimidin-4-yl)-2-oxopyridin-1(2H)-yl)methyl)pyrrolidine-1-carboxylate(1453854-02-8)

Safety Data

• Hazardous Substances Data: 1453854-02-8(Hazardous Substances Data)

Upstream product

• 1453851-73-4 4-(2-fluoropyridin-4-yl)-2-(methylthio)pyrimidine 
• 401815-98-3 2-fluoropyridin-4-ylboronic acid 
• 959236-97-6 4-bromo-2-methylsulfanylpyrimidine 
• 72925-16-7 (R)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid 
• 1453854-00-6 (3R)-tert-butyl-3-((4-chloro-3-fluorophenyl)(hydroxy)methyl)pyrrolidine-1-carboxylate 
• 1453851-57-4 4-(2-(methylthio)pyrimidin-4-yl)pyridin-2(1H)-one 
• 1453853-98-9 (R)-tert-butyl 3-(4-chloro-3-fluorobenzoyl)pyrrolidine-1-carboxylate 
• 1204677-54-2 (R)-tert-butyl-3-(methoxy(methyl)carbamoyl)pyrrolidine-1-carboxylate 

Downstream Products

• 1453854-06-2 (R)-tert-butyl-3-((R)-(4-chloro-3-fluorophenyl)(4-(2-(methylsulfonyl)pyrimidin-4-yl)-2-oxopyridin-1(2H)-yl)methyl)pyrrolidine-1-carboxylate 
• 1453848-37-7 1-((R)-(4-chloro-3-fluorophenyl)((R)-pyrrolidin-3-yl)methyl)-4-(2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one 

Relevant articles and documents

SERINE/THREONINE KINASE INHIBITORS

Compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative, pain and inflammatory diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.