1453867-84-9Relevant academic research and scientific papers
Stereocontrolled synthesis of trichodermatide A
Shigehisa, Hiroki,Suwa, Yoshihiro,Furiya, Naho,Nakaya, Yuki,Fukushima, Minoru,Ichihashi, Yusuke,Hiroya, Kou
supporting information, p. 3646 - 3649 (2013/05/21)
Hard core made easy: The pentacyclic core of trichodermatide A was stereoselectively synthesized from a bis(1,3-cyclohexanedione) derivative by a ring-closing reaction followed by an intramolecular ketal formation (see scheme; PPTS=pyridinium p-toluenesulfonate). The first total synthesis of trichodermatide A was then completed by the introduction of three hydroxy groups. Copyright
