145413-17-8

Basic information

• Product Name: (4'-Butyl[1,1'-biphenyl]-4-yl)-boronic acid
• Synonyms: (4'-Butyl[1,1'-biphenyl]-4-yl)-boronic acid;B-(4'-Butyl[1,1'-biphenyl]-4-yl)boronic acid;4'-butylbiphenyl-4-ylboronic acid
• CAS NO: 145413-17-8
• Molecular Formula: C16H19BO2
• Molecular Weight: 254.13186
• Mol File: 145413-17-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 157℃
• Boiling Point: 424.697 °C at 760 mmHg
• Flash Point: 210.65 °C
• Appearance: /
• Density: 1.09
• Storage Temp.: 2-8°C
• PKA: 8.61±0.17(Predicted)
• CAS DataBase Reference: (4'-Butyl[1,1'-biphenyl]-4-yl)-boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (4'-Butyl[1,1'-biphenyl]-4-yl)-boronic acid(145413-17-8)
• EPA Substance Registry System: (4'-Butyl[1,1'-biphenyl]-4-yl)-boronic acid(145413-17-8)

Safety Data

• Hazardous Substances Data: 145413-17-8(Hazardous Substances Data)

Usage

General Description

(4'-Butyl[1,1'-biphenyl]-4-yl)-boronic acid is a chemical compound used in organic synthesis and pharmaceutical research. It is a boronic acid derivative with a butyl-substituted biphenyl core structure. Boronic acids are important intermediates in organic chemistry, particularly for their role in Suzuki-Miyaura coupling reactions, which are widely used for the synthesis of complex organic molecules. The butyl-substituted biphenyl structure of this compound makes it a valuable building block for the synthesis of various organic molecules, especially in medicinal chemistry where it may be used in the development of new pharmaceuticals. Additionally, boronic acids have been studied for their potential applications in materials science and as components in sensors and other analytical methods.

Upstream product

• 63619-54-5 4-bromo-4'-(n-butyl)-2,2'-biphenyl 

Relevant articles and documents

Synthesis of thiophene/phenylene co-oligomers. V [1]. Functionalization at molecular terminals toward optoelectronic device applications

(Chemical Equation Presented) We report the synthesis of various thiophene/phenylene co-oligomers with a total number of thiophene and benzene (phenylene) rings of 5 and 6 with various terminal groups. Those terminal groups have been chosen from among alkyl groups, methoxy groups, trifluoromethyl groups, and cyano groups. The molecular backbone of these compounds comprises phenyl- or biphenylyl-capped thiophene (or oligothiophene) or an alternating co-oligomer. The synthesis is based on either the Suzuki coupling reaction or the Negishi coupling reaction. These reaction schemes enabled us to obtain the target compounds in high quality. In particular, the latter coupling method turned out to produce the compounds at a high yield. The terminal groups are expected to produce various functionalities based upon their electron donating character (alkyl groups and methoxy groups) or electron withdrawing character (trifluoromethyl groups and cyano groups). Additionally some of these groups bring about enhanced solubility. This will lead to the production of a diversity of modified compounds of thiophene/phenylene co-oligomers. To give an example that demonstrates usefulness of the target compounds, we present optoelectronic data that are associated with their device applications.