145414-66-0 Usage
Molecular structure
The compound has a complex molecular structure, consisting of a pyrimidine ring with a methyl group and a dioxolane ring with a hydroxymethyl group.
Stereochemistry
The compound has specific stereochemistry, with the 2S,4R configuration at the dioxolane ring.
Functional groups
The compound contains a hydroxymethyl group, a methyl group, and two carbonyl groups (one at each position 2 and 4 of the pyrimidine ring).
Potential applications
The compound is a potential antiviral agent and has been studied for its potential use in the treatment of cancer.
Pharmaceutical research
Due to its unique molecular structure and potential therapeutic properties, the compound may have applications in pharmaceutical research and drug development.
Molecular weight
The molecular weight of the compound is approximately 236.21 g/mol.
Stability
The stability of the compound under various conditions (e.g., temperature, pH, etc.) is not provided in the material, but it may be influenced by the presence of the dioxolane ring and the carbonyl groups.
Synthesis
The synthesis of the compound is not described in the material, but it likely involves the formation of the pyrimidine ring, the dioxolane ring, and the attachment of the hydroxymethyl and methyl groups.
Check Digit Verification of cas no
The CAS Registry Mumber 145414-66-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,4,1 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 145414-66:
(8*1)+(7*4)+(6*5)+(5*4)+(4*1)+(3*4)+(2*6)+(1*6)=120
120 % 10 = 0
So 145414-66-0 is a valid CAS Registry Number.
145414-66-0Relevant articles and documents
2-Substituted-4-substituted-1,3-dioxolanes and use thereof
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Page column 51 -52, (2010/11/29)
Nucleoside analogues containing a 1,3-dioxolane structure are suitable antiviral agents, particulary for the treatment of the HIV infections in mammals, especially humans. Examples of the nucleoside analogues include: cis-2-acetoxymethyl-4-(thymin-1′-yl)-1,3,-dioxolane, cis-2-hydroxymethyl-4-(thymin-1′-yl)-1,3-dioxolane, cis-2-benzoyloxymethyl-4-(cytosin-1′-yl)-1,3-dioxolane, and cis-2-hydroxymethyl-4-(cytosin-1′-yl)-1,3-dioxolane. These compounds can be in the form of their racemates or their separate enantiomers.
In situ complexation directs the stereochemistry of N-glycosylation in the synthesis of oxathiolanyl and dioxolanyl nucleoside analogues
Choi, Woo-Baeg,Wilson, Lawrence J.,Yeola, Suresh,Liotta, Dennis C.,Schinazi, Raymond F.
, p. 9377 - 9379 (2007/10/02)
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