1454271-85-2Relevant academic research and scientific papers
Synthesis of β-fluoroenones and their reductive rearrangement in aqueous media
He, Yan,Shen, Nana,Fan, Xuesen,Zhang, Xinying
, p. 8818 - 8823 (2013)
In this paper, a simple and efficient preparation of β-fluoroenones, as a mixture of E/Z isomers with the E-isomer as the main product, from 1,2-allenic ketones by using TBAF·3H2O in water as a nucleophilic fluorination agent has been developed. Moreover, in exploring the synthetic applications of β-fluoroenones, an unprecedented reductive defluorination rearrangement of β-fluoroenones toward enones under mild conditions in aqueous media was also discovered.
