145428-73-5

Basic information

• Product Name: Z-pGlu-His-Pro-NH-(CH₂)6-NH-Boc
• CAS NO: 145428-73-5
• Molecular Weight: 695.816
• Mol File: 145428-73-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Z-pGlu-His-Pro-NH-(CH₂)6-NH-Boc(CAS DataBase Reference)
• NIST Chemistry Reference: Z-pGlu-His-Pro-NH-(CH₂)6-NH-Boc(145428-73-5)
• EPA Substance Registry System: Z-pGlu-His-Pro-NH-(CH₂)6-NH-Boc(145428-73-5)

Safety Data

• Hazardous Substances Data: 145428-73-5(Hazardous Substances Data)

Upstream product

• 145428-72-4 Z-Pro-NH-(CH₂)6-NH-Boc 
• 24424-99-5 di-tert-butyl dicarbonate 
• 124-09-4 1,6-Hexanediamine 
• 149991-72-0 {6-[((S)-Pyrrolidine-2-carbonyl)-amino]-hexyl}-carbamic acid tert-butyl ester 
• 42533-68-6 Z-pGlu-His-OH 
• 51857-17-1 tert-butyl N-(6-aminohexyl)carbamate 

Relevant articles and documents

Enzyme immunoassay of thyrotropin releasing hormone (TRH)

A sensitive and specific double-antibody enzyme immunoassay (EIA) for a thyrotropin releasing hormone (TRH)-like immunoreactive substance has been developed. In order to synthesize TRH-labeled β-D-galactosidase (β-gal), a newly devised TRH derivative, pGlu-His-Pro-NH-(CH2)6-NH2 (TRH-Hex), was employed. TRH-Hex was linked to β-gal by the N-(ε-maleimidocaproyloxy) succinimide coupling procedure. For competitive reactions, the TRH antibody was incubated with standard TRH and TRH-Hex-β-gal (delayed addition). Free and antibody-bound enzyme hapten were separated by using an anti-rabbit immunoglobulin G coated immunoplate. Activity of the enzyme on the plate was fluorometrically determined. The present immunoassay allows detection of 0.8 to 100 pmol/well of TRH.