1454306-07-0

Basic information

• Product Name: 2-amino-4-(2,4-dichlorophenyl)-6-(1H-indol-3-yl)-4H-pyran-3,5-dicarbonitrile
• Synonyms: 2-amino-4-(2,4-dichlorophenyl)-6-(1H-indol-3-yl)-4H-pyran-3,5-dicarbonitrile
• CAS NO: 1454306-07-0
• Molecular Weight: 407.258
• Mol File: 1454306-07-0.mol

Chemical Properties

• CAS DataBase Reference: 2-amino-4-(2,4-dichlorophenyl)-6-(1H-indol-3-yl)-4H-pyran-3,5-dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-(2,4-dichlorophenyl)-6-(1H-indol-3-yl)-4H-pyran-3,5-dicarbonitrile(1454306-07-0)
• EPA Substance Registry System: 2-amino-4-(2,4-dichlorophenyl)-6-(1H-indol-3-yl)-4H-pyran-3,5-dicarbonitrile(1454306-07-0)

Safety Data

• Hazardous Substances Data: 1454306-07-0(Hazardous Substances Data)

Upstream product

• 874-42-0 2,4-dichlorobenzaldeyhde 
• 20356-45-0 3-(1H-indol-3-yl)-3-oxo-propionitrile 
• 109-77-3 malononitrile 

Relevant articles and documents

l-Proline catalyzed facile and efficient synthesis of functionalized indol-3-yl pyran derivatives by multi-component reactions

A simple and green synthetic method for preparation of functionalized indol-3-yl pyran derivatives was developed. The reactions were carried out by one-pot three-component synthesis of 3-cyanoacetyl indoles, malononitrile/cyanoacetate and various aldehydes/isatins/acenaphthenequinone in the presence of catalytic amount of l-proline. The advantages of this method included straightforward processing, excellent yields, broad substrate scope and environmental friendliness.

Facile and efficient synthesis of indol-3-yl substituted pyran derivatives via one-pot multicomponent reactions under ultrasonic irradiation

A series of polysubstituted indol-3-yl substituted pyran derivatives have been synthesized via one-pot multicomponent reactions of aldehydes, malononitrile with 3-cyanoacetyl indoles under ultrasonic irradiation. This method has the advantages of high yield, easy operation, short-reaction time, mild-reaction condition, and catalyst recyclability.