145440-11-5

Basic information

• Product Name: 9H-Purine-2,6-diamine, 9-[(2R,4R)-2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-dioxolan- 4-yl]-
• CAS NO: 145440-11-5
• Molecular Formula: C25H30N6O3Si
• Molecular Weight: 490.637
• Mol File: 145440-11-5.mol

Chemical Properties

• CAS DataBase Reference: 9H-Purine-2,6-diamine, 9-[(2R,4R)-2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-dioxolan- 4-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 9H-Purine-2,6-diamine, 9-[(2R,4R)-2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-dioxolan- 4-yl]-(145440-11-5)
• EPA Substance Registry System: 9H-Purine-2,6-diamine, 9-[(2R,4R)-2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-dioxolan- 4-yl]-(145440-11-5)

Safety Data

• Hazardous Substances Data: 145440-11-5(Hazardous Substances Data)

Upstream product

• 145440-02-4 (-)-(2R,4R)-2-amino-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-6-chloropurine 

Downstream Products

• 145514-04-1 DAPD 

Relevant articles and documents

1,3-Dioxolanylpurine nucleosides (2R,4R) and (2R,4S) with selective anti- HIV-1 activity in human lymphocytes

In order to study the structure-activity relationships of dioxolane nucleosides as potential anti-HIV-1 agents, various enantiomers of pure dioxolanylpurine nucleosides were synthesized and evaluated against HIV-1 in human peripheral blood mononuclear cel