1454577-96-8Relevant academic research and scientific papers
A novel base-induced isomerization gives access to unprecedented (E)-exo-glycals
Eppe, Guillaume,Dumitrescu, Lidia,Pierrot, Olivier,Li, Tianlei,Pan, Weidong,Vincent, Stephane P.
, p. 11547 - 11552 (2013)
Bump the base: This study reports the discovery of the base-induced Z-to-E isomerization of exo-glycals bearing an electron-withdrawing group (EWG). The scope of this novel transformation regarding the carbohydrate unit is also discussed. After elucidating the mechanism, preparation of novel (E)-exo- glycals was performed (TBS=tert-butyldimethylsilyl). Copyright
