145471-60-9

Upstream product

• 145471-55-2 12-benzyl-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizine-4-one 
• 145471-58-5 2-((2R,3S,12bS)-12-Benzyl-3-ethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-2-yl)-malonic acid dimethyl ester 
• 145471-56-3 12-Benzyl-3-ethyl-6,7,12,12b-tetrahydro-1H-indolo[2,3-a]quinolizine-4-thione 
• 145471-59-6 ((2S,3S,12bS)-12-Benzyl-3-ethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-2-yl)-acetic acid methyl ester 

Downstream Products

• 483-27-2 (+/-)-3-epi-dihydrocorynantheol 

Relevant academic research and scientific papers

New approaches to Corynanthe alkaloids involving the conjugate addition of dialkyl malonates to unsaturated thiolactams: Synthesis of (±)-3-epi-dihydrocorynantheol

Addition of dimethyl malonate to thiolactam 8 led to a mixture of Michael adducts 9 and 10 (6:1, respectively). Compound 9 has been converted in 4 steps into (±)-3-epi-dihydrocorynantheol 16.