145471-88-1Relevant academic research and scientific papers
Formal Total Syntheses of (-)Isoavenaciolide and (-)Ethisolide from L-Quebrachitol
Chida, Noritaka,Tobe, Takahiko,Suwama, Masami,Ohtsuka, Masami,Ogawa, Seiichiro
, p. 2667 - 2673 (2007/10/02)
The stereoselective conversions of the naturally occurring optically active cyclitol, L-quebrachitol 5, into the known synthetic intermediates, 3 and 4, for preparations of structurally interesting bislactones, (-)-isoavenaciolide 1 and (-)-ethisolide 2, respectively, are described.These bislactones, 3 and 4, were synthesized from the common intermediate 19, which was prepared by periodate oxidation of the bicyclic cyclitol derivative 17.
