1454818-64-4Relevant academic research and scientific papers
Rhodium-diphosphine ligand tetrafluoroborate and preparation method thereof
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Paragraph 0017, (2017/08/29)
The invention discloses a rhodium-diphosphine ligand tetrafluoroborate and a preparation method thereof. According to the method, quinquevalent phenylphosphonyl dichloride is used as a starting raw material; firstly, quinquevalent phosphoryl compounds are prepared; then, a chiral quinquevalent phosphoryl compound is obtained through kinetic resolution; the unstable trivalent phosphorus is avoided; meanwhile, the optical purity of the quinquevalent phosphorus is improved; the EE value can reach 97 or higher; the sufficient space is remained for the optical purity reduction due to subsequent quinquevalent phosphorus reduction and coupling, so that the purity and the yield of the prepared diphosphine ligand are very high; further, the rhodium-diphosphine ligand tetrafluoroborate prepared from the diphosphine ligand has high activity and good optical selectivity.
