14549-59-8

Basic information

• Product Name: 4-(4-Methyl-1-piperazinyl)-3-pyridinamine
• Synonyms: 4-(4-Methyl-1-piperazinyl)-3-pyridinamine
• CAS NO: 14549-59-8
• Molecular Formula: C10H16 N4
• Molecular Weight: 192.2608
• Mol File: 14549-59-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 361.6°Cat760mmHg
• Flash Point: 172.5°C
• Appearance: /
• Density: 1.142g/cm³
• Vapor Pressure: 2.05E-05mmHg at 25°C
• Refractive Index: 1.593
• PKA: 11.74±0.20(Predicted)
• CAS DataBase Reference: 4-(4-Methyl-1-piperazinyl)-3-pyridinamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Methyl-1-piperazinyl)-3-pyridinamine(14549-59-8)
• EPA Substance Registry System: 4-(4-Methyl-1-piperazinyl)-3-pyridinamine(14549-59-8)

Safety Data

• Hazardous Substances Data: 14549-59-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H16N4/c1-13-4-6-14(7-5-13)10-2-3-12-8-9(10)11/h2-3,8H,4-7,11H2,1H3

Upstream product

• 109-01-3 1-methyl-piperazine 
• 13091-23-1 4-chloro-3-nitropyridine 

Relevant articles and documents

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula (I) or a pharmaceutically acceptable salt, wherein the variables are as devined herein. Moreover, The compounds of this invention have formula (I-A) or a pharmaceutically acceptable salt, wherein the variables are as defined herein.