14549-75-8 Usage
General Description
1,4-Bis[2-(2-pyridyl)ethyl]piperazine is a chemical compound with the molecular formula C18H26N4. It is a piperazine derivative with two pyridine rings attached to the piperazine core. 1,4-Bis[2-(2-pyridyl)ethyl]piperazine is commonly used as a ligand in coordination chemistry and as a building block for the synthesis of various coordination complexes. It has potential applications in pharmaceuticals, agriculture, and materials science. 1,4-Bis[2-(2-pyridyl)ethyl]piperazine is also being studied for its potential biological and pharmacological activities, with research indicating its potential as an anticancer and antiviral agent. However, its precise mechanism of action and potential side effects are still under investigation.
Check Digit Verification of cas no
The CAS Registry Mumber 14549-75-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,5,4 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 14549-75:
(7*1)+(6*4)+(5*5)+(4*4)+(3*9)+(2*7)+(1*5)=118
118 % 10 = 8
So 14549-75-8 is a valid CAS Registry Number.
InChI:InChI=1/C18H24N4/c1-3-9-19-17(5-1)7-11-21-13-15-22(16-14-21)12-8-18-6-2-4-10-20-18/h1-6,9-10H,7-8,11-16H2
14549-75-8Relevant articles and documents
Anti-Markonikov reactions, 6. Rhodium-catalyzed amination of vinylpyridines: Hydroamination versus oxidative amination
Beller, Matthias,Trauthwein, Harald,Eichberger, Martin,Breindl, Claudia,Mueller, Thomas E.
, p. 1121 - 1132 (2007/10/03)
Cationic rhodium complexes catalyze the amination of 2- and 4- vinylpyridine with secondary amines. Depending on the substrate and the reaction conditions either oxidative amination to yield the corresponding enamines 1a-8a or hydroamination to give 2-aminoethylpyridines 1b-8b occurs. In all cases products with anti-Markovnikov regioselectivity are obtained. For mechanistic studies novel cationic complexes of rhodium(I)-containing cyclooctadiene and vinylpyridine 12 as well as complexes containing cyclooctadiene, vinylpyridine, and morpholine 13 were prepared and characterized by NMR spectroscopy and X-ray diffraction analysis.