1455089-20-9

Basic information

• Product Name: 3-(R)-[(1-cyano-4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]-5-phenylpentanoic acid
• Synonyms: 3-(R)-[(1-cyano-4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]-5-phenylpentanoic acid
• CAS NO: 1455089-20-9
• Molecular Weight: 481.508
• Mol File: 1455089-20-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(R)-[(1-cyano-4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]-5-phenylpentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(R)-[(1-cyano-4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]-5-phenylpentanoic acid(1455089-20-9)
• EPA Substance Registry System: 3-(R)-[(1-cyano-4-hydroxy-7-phenoxyisoquinoline-3-carbonyl)amino]-5-phenylpentanoic acid(1455089-20-9)

Safety Data

• Hazardous Substances Data: 1455089-20-9(Hazardous Substances Data)

Upstream product

• 1455091-23-2 1-cyano-4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid methyl ester 
• 147228-37-3 (3R)-3-amino-5-phenylpentanoic acid 

Relevant articles and documents

4 -HYDROXY- ISOQUINOLINE COMPOUNDS AS HIF HYDROXYLASE INHIBITORS

The present invention relates to novel compounds of formula (I), and compositions capable of inhibiting PHD1 enzyme activity selectively over other isoforms, for example, PHD2 and/or PHD3 enzymes. The invention also relates to compounds of formula (I) for use in disorders such as muscle degeneration, colitis, IBD, and certain ischemias.