145510-85-6 Usage
General Description
The chemical compound [2-(4-bromophenyl)-4-hydroxy-5-oxo-1-phenyl-2,5-dihydro-1H-pyrrol-3-yl]acetic acid is a synthetic organic compound with a complex molecular structure. It contains a phenyl ring, a pyrrole ring, and a carboxylic acid group. The compound has both hydroxy and ketone functional groups, as well as a bromine atom attached to the phenyl ring. It is commonly used as a building block for the synthesis of various pharmaceutical and bioactive compounds due to its versatile reactivity and potential therapeutic properties. Additionally, its unique structure makes it valuable for medicinal chemistry research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 145510-85-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,5,1 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 145510-85:
(8*1)+(7*4)+(6*5)+(5*5)+(4*1)+(3*0)+(2*8)+(1*5)=116
116 % 10 = 6
So 145510-85-6 is a valid CAS Registry Number.
145510-85-6Relevant articles and documents
SYNTHESIS AND BIOLOGICAL ACTIVITY OF 1,5-DIARYL-3-ARYLAMINO-4-CARBOXYMETHYL-2,5-DIHYDRO-2-PYRROLONES AND 1,5-DIARYL-4-CARBOXYMETHYLTETRAHYDROPYRROLE-2,3-DIONES
Gein, V.L.,Popov, A.V.,Kolla, V.E.,Popova, N.A.,Potemkin, K.D.
, p. 343 - 346 (2007/10/02)
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REACTION OF α-KETOGLUTARIC ACID WITH SCHIFF BASES
Gein, V. L.,Popov, A. V.,Andreichikov, Yu. S.
, p. 2291 - 2295 (2007/10/02)
1,5-Diaryl-3-arylamino-4-carboxymethyl-2,5-dihydropyrrol-2-ones were synthesized in the reaction of α-ketoglutaric acid with Schiff bases. Their hydrolysis in concentrated hydrochloric acid results in 1,5-diaryl-3-hydroxy-4-carboxymethyl-2,5-dihydropyrrol-2-ones. These latter are converted into the initial compounds when treated with arylamines. The heating of 1,5-diaryl-4-methoxycarbonyl-2,5-dihydropyrrol-2-ones and their 3-arylamino derivatives above the melting point leads to their decarboxylation, while the treatment with diphenyldiazomethane converts them into the corresponding benzhydryl ethers.
