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CAS

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1455272-61-3

4-(4-methylthiophenyl)-5-(phenyl)-2-(methylthio)-thiazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1455272-61-3 Structure

  • Basic information

    1. Product Name: 4-(4-methylthiophenyl)-5-(phenyl)-2-(methylthio)-thiazole
    2. Synonyms:
    3. CAS NO:1455272-61-3
    4. Molecular Formula:
    5. Molecular Weight: 329.511
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1455272-61-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(4-methylthiophenyl)-5-(phenyl)-2-(methylthio)-thiazole(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(4-methylthiophenyl)-5-(phenyl)-2-(methylthio)-thiazole(1455272-61-3)
    11. EPA Substance Registry System: 4-(4-methylthiophenyl)-5-(phenyl)-2-(methylthio)-thiazole(1455272-61-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1455272-61-3(Hazardous Substances Data)

1455272-61-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1455272-61-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,5,2,7 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1455272-61:
(9*1)+(8*4)+(7*5)+(6*5)+(5*2)+(4*7)+(3*2)+(2*6)+(1*1)=163
163 % 10 = 3
So 1455272-61-3 is a valid CAS Registry Number.

1455272-61-3Downstream Products

1455272-61-3Relevant articles and documents

Synthesis, cytotoxic evaluation, and molecular docking study of 4,5-diaryl-thiazole-2-thione analogs of combretastatin A-4 as microtubule-binding agents

Salehi, Marjan,Ostad, Seyed Nasser,Riazi, Gholam Hossein,Assadieskandar, Amir,Cheraghi-Shavi, Tayebeh,Shafiee, Abbas,Amini, Mohsen

, p. 1465 - 1473 (2014/03/21)

A series of combretastatin A-4 analogs in which cis-olefinic bond replaced by thiazole ring were prepared by reaction of α-bromo-1,2-(p-substituted) diaryl-1-ethanones and dithiocarbamate derivatives. The cytotoxicity of these compounds was determined against three cancer cell lines (HT-29), (MCF-7), (AGS) as well as fibroblastic cell line (NIH-3T3) using MTT assay. Inhibition of tubulin polymerization for some potent compounds was evaluated. These biological studies proved that 6j and 6o were the most potent compounds in this series. Furthermore 2-(methylthio)-substituted compounds show moderate or no activity. Docking studies involving 6j and 6o demonstrated that this analogs could be successfully docked in the colchicine binding site of α,β-tubulin.

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