1455342-72-9Relevant academic research and scientific papers
Synthesis and structure evaluation of new complex butylarylpiperazin-1-yl derivatives
Szulczyk, Daniel,Bielenica, Anna,Dobrowolski, Michal A.,Dobrzycki, Lukasz,Krawiecka, Mariola,Kuran, Bozena,Struga, Marta
, p. 1519 - 1536 (2014/03/21)
A series of arylpiperazine derivatives of 1,16-diphenyl-19-azahexacyclo- [14.5.1.02,15.03,8.09,14.017,21] docosa-2,3,5,7,8,9,11,13,14-nonaene-18,20,22-trione and 4,10-diphenyl-1H,2H,3H, 5H-indeno[1,2-f]isoindole-1,3,5-trione was synthesized. The pharmacological profile of compound 4 at the 5-HT1A receptor was measured by binding assay. The title compounds were tested in cell-based assay against the human immunodeficiency virus type-1. The X-ray crystallographic studies of derivatives 2, 6, 7, 11, 19, and 20 were presented.
