14554-00-8

Usage

Derivative of

Naphthalene

Contains

Fluorine atom and an amino group

Common uses

Organic synthesis and pharmaceutical research

Unique structure

Contributes to its reactivity

Applications

Development of new drugs and materials

Known for

Fluorescence properties

Applications of fluorescence

Analytical chemistry and biological imaging

Hazardous material

Requires special precautions for storage and handling

Upstream product

• 5385-52-4 1-Fluor-2-nitro-naphthalin 
• 19580-15-5 N-(1-fluoronaphthalen-2-yl) acetamide 
• 607-23-8 2-nitro-1-naphthylamine 

Relevant academic research and scientific papers

Rapid Access to Fluorinated Anilides via DAST-Mediated Deoxyfluorination of Arylhydroxylamines

A new strategy for the synthesis of fluorinated anilides in the absence of metals and oxidants has been developed. This deoxyfluorination of N-arylhydroxylamines with diethylaminosulfur trifluoride (DAST) proceeded smoothly under mild conditions, and the

SUBSTITUTED AMINO PHENYLACETIC ACIDS, DERIVATIVES THEREOF, THEIR PREPARATION AND THEIR USE AS CYCLOOXYGENASE 2 (COX-2) INHIBITORS

Compounds of formula (I) wherein R is hydrogen, lower alkyl, (C3-C8)cycloalkyl, hydroxy, halo, lower alkoxy, trifluoromethoxy, trifluoromethyl or cyano; and A is biaryl, optionally substituted β-naphthyl, bicyclic heterocyclic aryl, (C3-C6)cycloalkylmonocyclic carbocyclic aryl, or (C5 or C6)cycloalkane fused-monocyclic carbocyclic aryl; pharmaceutically acceptable salts thereof, and pharmaceutically acceptable esters thereof; which are useful for the treatment of COX-2 dependent disorders.