145545-15-9 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
Phosphoric acid, bis(1,1-dimethylethyl) 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl ester is used as a potential therapeutic agent in pharmaceutical research and drug development due to its potential therapeutic properties.
Used in Chemical Synthesis and Compound Screening:
In the field of medicinal chemistry, PDB is used in chemical synthesis and compound screening for the development of new drugs and therapeutic agents.
Used in Molecular Biology Research:
Phosphoric acid, bis(1,1-dimethylethyl) 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl ester is also used in molecular biology research as a tool for studying various biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 145545-15-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,5,4 and 5 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 145545-15:
(8*1)+(7*4)+(6*5)+(5*5)+(4*4)+(3*5)+(2*1)+(1*5)=129
129 % 10 = 9
So 145545-15-9 is a valid CAS Registry Number.
145545-15-9Relevant academic research and scientific papers
Synthesis of combretastatin A-4 prodrugs and trans-isomers thereof
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Page/Page column 12-13, (2008/06/13)
The present invention relates to novel water-soluble, stable derivatives of combretastatin A-4, and novel synthesis methods therefore. The combretastatin A-4 prodrugs described herein appear to be useful in the treatment of neoplastic disease.
Synthesis of water-soluble prodrugs of the cytotoxic agent Combretastatin A4
Bedford, Simon B.,Quarterman, Charmaine P.,Rathbone, Daniel L.,Slack, John A.,Griffin, Roger J.,Stevens, Malcolm F. G.
, p. 157 - 160 (2007/10/03)
Water-soluble phosphate and glycine carbamate prodrugs of the cytotoxic agent Combretastatin A4 (1) have been prepared. The phosphate prodrug was degraded slowly in plasma at 37°C. The degradation was accelerated by the addition of alkaline phosphatase.
