145545-46-6Relevant academic research and scientific papers
An enantioselective approach to ring A of taxol using the Wieland-Miescher ketone
Golinski, Miroslaw,Vasudevan, Sundar,Floresca, Rey,Brock, Carolyn P.,Watt, David S.
, p. 55 - 58 (1993)
The selective protection of the S-(+)-enantiomer of the Wieland Miescher ketone (2) as the tert-butyldimethylsilyl-protected cyanohydrin 7 and the oxidative cleavage of an α-ketol 8 that was derived from 7 provided a model 10 for the A ring of the taxol (
Addition of tert-Butyldimethyl- or tert-Butyldiphenylsilyl Cyanide to Hindered Ketones
Golinski, Miroslaw,Brock, Carolyn P.,Watt, David S.
, p. 159 - 164 (2007/10/02)
The addition of trimethylsilyl cyanide (TMSCN), tert-butyldimethylsilyl cyanide (TBDMSCN) or tert-butyldiphenylsilyl cyanide (TBDPSCN) to sterically hindered ketones proceeded in good yield under catalysis by Lewis acids (ZnI2, CH2Cl2, 25 deg C) or bases
A SELECTIVE ONE-CARBON RING EXPANSION REACTION OF 1-SILOXYCYCLOALKANECARBALDEHYDES CATALYZED BY A LEWIS ACID
Matsuda, Toyoharu,Tanino, Keiji,Kuwajima, Isao
, p. 4267 - 4270 (2007/10/02)
Under the influence of a Lewis acid, 1-siloxycycloalkanecarbaldehydes undergo one-carbon ring enlargement reaction to afford the corresponding 2-siloxycycloalkanones in good yields.Regiochemistry of this rearrangement reaction has also been examined, and
