145593-60-8

Basic information

• Product Name: N-(2-chloroethyl)-N-(1-buten-3-yl)benzylamine
• Synonyms: N-(2-chloroethyl)-N-(1-buten-3-yl)benzylamine
• CAS NO: 145593-60-8
• Molecular Weight: 223.746
• Mol File: 145593-60-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-chloroethyl)-N-(1-buten-3-yl)benzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chloroethyl)-N-(1-buten-3-yl)benzylamine(145593-60-8)
• EPA Substance Registry System: N-(2-chloroethyl)-N-(1-buten-3-yl)benzylamine(145593-60-8)

Safety Data

• Hazardous Substances Data: 145593-60-8(Hazardous Substances Data)

Upstream product

• 37857-30-0 N-benzyl(but-3-en-2-yl)amine 
• 133957-65-0 N-(but-3-en-2-yl)-benzamide 

Downstream Products

• 145593-68-6 (2R,3R)-1-Benzyl-2,3-dimethyl-pyrrolidine 
• 145593-68-6 (2R,3S)-1-Benzyl-2,3-dimethyl-pyrrolidine 

Relevant articles and documents

Transition Metal-Catalyzed Radical Cyclizations: A Low-Temperature Process for the Cyclization of N-Protected N-Allyltrichloroacetamides to Trichlorinated γ-Lactams and Application to the Stereoselective Preparation of β,γ-Disubstituted γ-Lactams

Cyclisations of N-substituted N-allyltrichloroacetamides, where the substituent is an alkyl, Cbz, Boc, Ts, or Ms group, are catalyzed by a 1:1 mixture of CuCl and bipyridine to give the corresponding β,γ-trichlorinated γ-lactams in high yields.The reactions proceed at temperatures from -78 deg C to room temperature.Cyclizations of N-allyltrichloroacetamides of acyclic secondary allylic amines are achieved with good selectivity; the cis/trans ratios of the γ-lactams formed were dependent on the substituents on the nitrogen atom.The stereochemical outcome is compared with that of free-radical cyclization.