145593-71-1

Basic information

• Product Name: 1-(2',3'-Dideoxy-β-D-glucopyranosyl)uracil
• Synonyms: 1-(2',3'-Dideoxy-β-D-glucopyranosyl)uracil
• CAS NO: 145593-71-1
• Molecular Weight: 242.232
• Mol File: 145593-71-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2',3'-Dideoxy-β-D-glucopyranosyl)uracil(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2',3'-Dideoxy-β-D-glucopyranosyl)uracil(145593-71-1)
• EPA Substance Registry System: 1-(2',3'-Dideoxy-β-D-glucopyranosyl)uracil(145593-71-1)

Safety Data

• Hazardous Substances Data: 145593-71-1(Hazardous Substances Data)

Upstream product

• 136020-18-3 1-(2,3-dideoxy-erythro-β-D-hexopyranosyl)cytosine 

Downstream Products

• 145594-13-4 1-<2',3'-Dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>uracil 
• 145594-06-5 1-<4'-O-<(2-Cyanoethoxy)(diisopropylamino)phosphino>-2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-β-D-glucopyranosyl>uracil 
• 145594-03-2 1-<2',3'-Dideoxy-4'-O-<(diisopropylamino)(methoxy)phosphino>-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-β-D-glucopyranosyl>uracil 
• 145610-82-8 Succinic acid mono-[(2R,3S,6R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-6-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-pyran-3-yl] ester 
• 145593-98-2 1-<2',3'-Dideoxy-6'-<(4,4'-dimethoxytriphenyl)methyl>-β-D-glucopyranosyl>uracil 

Relevant articles and documents

Investigation of the kinetics of degradation of hexopyranosylated cytosine nucleosides using liquid chromatography

Liquid chromatography was used to follow the degradation of hexopyranosylated cytosine nucleosides in buffers of acid, neutral and alkaline pH and of constant ionic strength. The compounds were found to degrade by hydrolysis to cytosine and/or by deamination to the corresponding uracil nucleosides. Degradation in acid is influenced by the number of sugar hydroxyl groups, presence of sugar double bonds and the type of anomer. Stability of some of the compounds was compared with that of related thymine nucleosides. Temperature studies support a unimolecular mechanism of hydrolysis at pH 1.22.