1456-15-1Relevant academic research and scientific papers
Michael addition of aromatic heterocyclic compounds to α,β-unsaturated ketones. 3-Oxoalkylation of furans, indoles and thiophenes.
Dujardin, Gilles,Poirier, Jean-Marie
, p. 900 - 909 (2007/10/02)
The Lewis-acid catalyzed Michael-type addition of aromatic heterocyclic compounds, such as furans, indoles and thiophenes, to α,β-unsaturated ketones (including methyl vinyl ketone) was performed in mild conditions in the presence of boron trifluoride etherate and an alcohol.Rosethiophene was prepared in a synthesis involving a few steps. - Keywords: Michael addition / boron trifluoride etherate / but-3-ene-2-one / 3-oxoalkylation / rosethiophene
