145609-47-8

Upstream product

• 112-16-3 n-dodecanoyl chloride 
• 97562-24-8 allyl 2-deoxy-4,6-O-isopropylidene-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside 
• 140236-13-1 allyl 2-deoxy-3-O-(N-dodecanoylglycyl)-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside 
• 7596-88-5 N-dodecanoylglycine 
• 140236-14-2 allyl 2-deoxy-4-O-diphenylphosphono-3-O-(N-dodecanoylglycyl)-6-O-(2,2,2-trichloroethoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside 

Downstream Products

• 123574-56-1 1-O-acetyl-2-deoxy-4-O-diphenylphosphono-3-O-(N-dodecanoylglycyl)-6-O-(2,2,2-trichloroethoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-D-glucopyranose 
• 133940-55-3 Dodecanoylamino-acetic acid (2R,3R,4R,5S,6R)-2-bromo-5-(diphenoxy-phosphoryloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-6-(2,2,2-trichloro-ethoxycarbonyloxymethyl)-tetrahydro-pyran-4-yl ester 

Relevant academic research and scientific papers

Synthesis and biological activities of lipid A analogs: Modification of a glycosidically bound group with chemically stable polar acidic groups and lipophilic groups on the disaccharide backbone with tetradecanoyl or N-dodecanoylglycyl groups

Six novel lipid A analogs were synthesized. The first two analogs, 4 and 5, have an α-glycosidically bound carboxymethyl or 1,3-dicarboxyisopropyl group on the disaccharide backbone with four tetradecanoyl groups. The next three analogs, 6, 7 and 8, have