145653-13-0Relevant academic research and scientific papers
Asymmetric Epoxidation and Kinetic Resolution of Allylic Phosphine Oxides
Clayden, Jonathan,Warren, Stuart
, p. 2811 - 2824 (2007/10/02)
Allylic alcohols bearing a diphenylphosphinoyl group undergo asymmetric epoxidation with excellent enantioselectivity, and can undergo kinetic resolution with good diastereoselectivity, with the diphenylphosphinoyl group exerting an anti-directing effect
Asymmetric epoxidations and kinetic resolutions of δ-hydroxy allylic phosphine oxides
Clayden,Collington,Warren
, p. 7043 - 7046 (2007/10/02)
δ-Hydroxy allylic phosphine oxides 5 undergo asymmetric epoxidation to yield epoxy alcohols 6 with high enantio- and diastereoselectivity. Kinetic resolutions are also successful, even with a chiral centre remote from the allylic hydroxyl, if that chiral
