145657-39-2

Upstream product

• 367-25-9 2,4-difluorophenylamine 
• 504-02-9 1,3-cylohexanedione 

Downstream Products

• 1220515-78-5 3-[(2,4-difluorophenyl)(phenyl)amino]-2-iodocyclohex-2-enone 
• 1220515-91-2 3-[(2,4-difluorophenyl)(4-nitrophenyl)amino]-2-iodocyclohex-2-enone 
• 1260425-52-2 3-[(2,4-difluorophenyl)(methyl)amino]cyclohex-2-enone 

Relevant academic research and scientific papers

Concurrent α-iodination and N-arylation of cyclic β-enaminones

A variety of N-substituted 3-aminocyclohex-2-enones were converted into the corresponding N-arylated α-iodo enaminones in high yields via concurrent N-iodination and N-arylation mediated by ArI(OAc)2. A mechanism is postulated to account for the reaction differences between the cyclic and the acyclic -enaminones, which undergo predominant β-acetoxylation under the same reaction conditions.