1456776-33-2Relevant academic research and scientific papers
Synthesis and bioassay of ethyl-2- (2-((Diethoxyphosphoryl) (Aryl) Methylamino)thiazol-4-Yl)-2-(Methoxyimino)acetates
Sudha, S. Santhi,Sundar, Ch. Syama,Reddy, N. Bakthavatchala,Rao, K. Uma Maheswara,Jaya Prakash,Reddy, C. Suresh
, p. 1402 - 1411 (2013/10/08)
A simple, efficient, and environmentally benign methodology has been accomplished for the synthesis of α-aminophosphonates by one-pot three-component reaction of ethyl-2-amino-α-(methoxy-imino)-4- thiazoleacetate, aldehydes, and diethylphosphite by using Amberlyst-15 as catalyst at room temperature under solvent-free conditions. Their chemical structures were characterized by infrared (IR), NMR (1H, 13C & 31P), mass spectral, and elemental analysis. All the title compounds were screened for radical-scavenging activity by 1,1-diphenyl-2-picrylhydrazyl (DPPH), nitic oxide (NO), and hydrogen peroxide (H2O2) methods. Supplementary materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements for the following free supplemental files: Additional text and figures.
