1456789-14-2

Upstream product

• 33906-30-8 2-hydrazinobenzoic acid hydrochloride 
• 2338-75-2 4-(Trifluoromethyl)phenylacetonitrile 

Downstream Products

• 1456789-38-0 3-(4-trifluoromethylphenyl)-5-(2-dimethylaminoethylamino)pyrazolo[1,5-a]quinazoline hydrochloride 
• 1456789-39-1 3-(4-trifluoromethylphenyl)-5-(2-diethylaminoethylamino)pyrazolo[1,5-a]quinazoline hydrochloride 
• 1456789-40-4 3-(4-trifluoromethylphenyl)-5-(2-dimethylaminopropyl-1-amino)pyrazolo[1,5-a]quinazoline hydrochloride 
• 1456789-41-5 ClH*C₂₃H₁₉F₃N₆ 
• 1456789-17-5 5-chloro-3-(4-trifluoromethylphenyl)pyrazolo[1,5-a]quinazolin-5(4H)-one 
• 1456789-35-7 5-(2-dimethylamino-1-ethoxy)-3-(4-trifluoromethylphenyl)pyrazolo[1,5-a]quinazoline hydrochloride 
• 1456789-36-8 5-(2-diethylamino-1-ethoxy)-3-(4-trifluoromethylphenyl)pyrazolo[1,5-a]quinazoline hydrochloride 
• 1456789-37-9 5-(3-dimethylamino-1-propoxy)-3-(4-trifluoromethylphenyl)pyrazolo[1,5-a]quinazoline hydrochloride 

Relevant academic research and scientific papers

Phenylpyrazolo[1,5-a]quinazolin-5(4 H)-one: A suitable scaffold for the development of noncamptothecin topoisomerase i (Top1) inhibitors

In search for a novel chemotype to develop topoisomerase I (Top1) inhibitors, the pyrazolo[1,5-a]quinazoline nucleus, structurally related to the indenoisoquinoline system precursor of well-known Top1 poisons, was variously decorated (i.e., a substituted