1456798-99-4

Basic information

• Product Name: 5-(4-fluoro-3-methylphenyl)-2,2-dimethyl-4H-benzo[d][1,3]-dioxin-4-one
• Synonyms: 5-(4-fluoro-3-methylphenyl)-2,2-dimethyl-4H-benzo[d][1,3]-dioxin-4-one
• CAS NO: 1456798-99-4
• Molecular Weight: 286.303
• Mol File: 1456798-99-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(4-fluoro-3-methylphenyl)-2,2-dimethyl-4H-benzo[d][1,3]-dioxin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-fluoro-3-methylphenyl)-2,2-dimethyl-4H-benzo[d][1,3]-dioxin-4-one(1456798-99-4)
• EPA Substance Registry System: 5-(4-fluoro-3-methylphenyl)-2,2-dimethyl-4H-benzo[d][1,3]-dioxin-4-one(1456798-99-4)

Safety Data

• Hazardous Substances Data: 1456798-99-4(Hazardous Substances Data)

Upstream product

• 1236563-13-5 C₁₀H₉IO₃ 
• 139911-27-6 4-fluoro-3-methylphenyl boronic acid 

Relevant articles and documents

Efficient synthesis of functionalized 6-arylsalicylates via microwave-promoted Suzuki cross-coupling reaction

Functionalized 6-arylsalicylate substructures occur in a variety of pharmacologically relevant natural products and bioactive compounds. They are also broadly used as important intermediates in organic synthesis. Traditional synthetic methods have suffered from some drawbacks, such as relatively harsh reaction conditions, narrow range of substrates, and poor yields. Utilizing microwave irradiation, the synthesis of functionalized 6-arylsalicylates via a Suzuki cross-coupling has been developed with a wide range of substrates. Almost all the reactions proceeded smoothly and afforded moderate to excellent yields of products, which indicated that electronic effects and steric modifications have little effect on this reaction.