1456809-29-2

Upstream product

• 90-33-5 7-hydroxy-4-methyl-chromen-2-one 
• 2555-28-4 4-methyl-7-methoxy-2H-1-benzopyran-2-one 
• 75908-67-7 3-bromo-7-methoxy-4-methylcoumarin 
• 2374-05-2 4-bromo-2,6-dimethyl-phenol 
• 1456809-35-0 5-bromo-2-((2-methoxyethoxy)methoxy)-1,3-dimethylbenzene 
• 1456809-36-1 2-((2-methoxyethoxy)methoxy)-1,3-dimethyl-5-vinylbenzene 
• 1456809-27-0 (E)-3-(4-hydroxy-3,5-dimethylstyryl)-7-methoxy-4-methyl-2H-chromen-2-one 
• 1456809-41-8 (E)-7-methoxy-3-(4-((2-methoxyethoxy)methoxy)-3,5-dimethylstyryl)-4-methyl-2H-chromen-2-one 

Relevant academic research and scientific papers

Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors

We describe coumarin derivatives that are non-fluorescent in aqueous buffers and that very selectively bind to transthyretin (TTR) in complex biological environments potently inhibiting TTR amyloidogenesis while also exhibiting sensitive off-on fluorescen