1456809-46-3

Upstream product

• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 94719-81-0 ω-formyl-4'-methoxy-2'-hydroxyacetophenone 
• 59887-92-2 5-hydroxy-7-methoxy-4H-chromen-4-one 
• 1388223-86-6 C₁₅H₁₉NO₃ 
• 1201816-71-8 5-(2-hydroxy-4-methoxybenzoyl)-1-o-tolylphenylpyridin-2(1H)-one 
• 874-60-2 4-methyl-benzoyl chloride 

Relevant academic research and scientific papers

Design and synthesis of novel 2′-hydroxy group substituted 2-pyridone derivatives as anticancer agents

We have synthesized a series of novel 2-pyridone derivatives with 1,2,3-triazole and evaluated their antitumor activities in vitro. The bioassays showed that the majority of the resultant compounds exerted inhibitory effects on six human cancer cell lines to various extents. In particular, compound 10k showed the best anti-tumor activities (IC50 values of A549, HeLa and SW480 cancer cell lines were 0.86 ± 0.17 mM, 0.54 ± 0.23 mM and 0.21 ± 0.13 mM, respectively).