145681-36-3Relevant academic research and scientific papers
Copper(I)-Catalyzed Enantioselective 1,6-Borylation of α,β,γ,δ-Unsaturated Phosphonates
Lee, Hyesu,Yun, Jaesook
, p. 7961 - 7964 (2019/01/14)
Copper(I)-catalyzed asymmetric 1,6-borylation of 1,3-dienylphosphonates was achieved using (S,S)-Ph-BPE as a chiral ligand. Regio-, stereo-, and enantioselective borylation successfully proceeded to afford phosphonate-containing allylboronates, with high enantioselectivity up to 97% ee. Further applications of the resulting products generated a valuable phosphonate analogue of γ-butyrolactone.
Asymmetric Epoxidation and Kinetic Resolution of Allylic Phosphine Oxides
Clayden, Jonathan,Warren, Stuart
, p. 2811 - 2824 (2007/10/02)
Allylic alcohols bearing a diphenylphosphinoyl group undergo asymmetric epoxidation with excellent enantioselectivity, and can undergo kinetic resolution with good diastereoselectivity, with the diphenylphosphinoyl group exerting an anti-directing effect
Asymmetric epoxidations and kinetic resolutions of δ-hydroxy allylic phosphine oxides
Clayden,Collington,Warren
, p. 7043 - 7046 (2007/10/02)
δ-Hydroxy allylic phosphine oxides 5 undergo asymmetric epoxidation to yield epoxy alcohols 6 with high enantio- and diastereoselectivity. Kinetic resolutions are also successful, even with a chiral centre remote from the allylic hydroxyl, if that chiral
