1456816-72-0

Basic information

• Product Name: N'-(4-hydroxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide
• Synonyms: N'-(4-hydroxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide
• CAS NO: 1456816-72-0
• Molecular Weight: 418.256
• Mol File: 1456816-72-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N'-(4-hydroxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(4-hydroxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide(1456816-72-0)
• EPA Substance Registry System: N'-(4-hydroxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide(1456816-72-0)

Safety Data

• Hazardous Substances Data: 1456816-72-0(Hazardous Substances Data)

Upstream product

• 1456816-57-1 ethyl 5-(1,2-diselenolan-3-yl)pentanoate 
• 1456816-58-2 5-(1,2-diselenolan-3-yl)pentanehydrazide 
• 123-08-0 4-hydroxy-benzaldehyde 
• 6708-13-0 5-(1,2-diselenolan-3-yl)pentanoic acid 
• 1070-64-0 6,8-dichlorooctanoic acid ethyl ester 
• 1451075-56-1 sodium 6,8-dichlorooctanoate 

Relevant articles and documents

Synthesis and Anticancer Activity of 5-(1,2-Diselenolan-3-Yl)pentanoic Acid and its Derivatives

A green and high-yielding synthetic route for the preparation of 5-(1,2-diselenolan-3-yl)pentanoic acid (SeA) was reported. Some SeA derivatives, N′-substituted benzylidene-5-(1,2-diselenolan-3-yl)pentanehydrazide, were prepared, and they were screened for their anticancer activity against human breast MCF-7, leukemia HL-60, cervixuterus Hela, and placental villus Bewo cancer cell lines. The minimum inhibitory concentrations (MICs) of the synthetic compounds showed moderate anticancer activity at low concentrations (0.5-5 μg/mL).