1456887-70-9Relevant academic research and scientific papers
Asymmetric synthesis of 3-spirocyclopropyl-2-oxindoles via intramolecular trapping of chiral aza-ortho-xylylene
Dou, Xiaowei,Yao, Weijun,Zhou, Bo,Lu, Yixin
, p. 9224 - 9226 (2013)
Chiral aza-ortho-xylylene intermediates were efficiently generated from 3-chloro-3-substituted oxindole precursors. The first intramolecular trapping of chiral aza-ortho-xylylene intermediates led to a highly asymmetric synthesis of 3-spirocyclopropyl-2-oxindoles.
