1456936-28-9Relevant academic research and scientific papers
One-pot three-component synthesis of indole-3-glyoxyl derivatives and indole-3-glyoxyl triazoles
Stefani, Hélio A.,Vasconcelos, Stanley N.S.,Souza, Frederico B.,Manarin, Flávia,Zukerman-Schpector, Julio
supporting information, p. 5821 - 5825 (2013/10/01)
A general and efficient reaction of indole with oxalyl chloride and nucleophiles providing indole-3-glyoxyl derivatives has been developed in mild conditions. In the same fashion, the other reaction involved the addition of organic azides leading to the synthesis of indole-3-glyoxyl-1,2,3-triazoles, which proceeds smoothly generating the products in moderate to high yields.
