1457-48-3 Usage
Ketone derivative
A ketone derivative is a compound derived from ketones, which are organic compounds containing a carbonyl group (C=O) bonded to two carbon atoms. In this case, 1-phenyl-2-(1H-pyrazol-1-yl)Ethanone has a carbonyl group attached to a phenyl group and a pyrazole ring.
Phenyl group
A phenyl group is a carbon-based functional group consisting of a six-membered aromatic ring with five hydrogen atoms and one substituent attached to it. In 1-phenyl-2-(1H-pyrazol-1-yl)Ethanone, the phenyl group is attached to the carbonyl group.
Pyrazole ring
A pyrazole ring is a five-membered aromatic heterocyclic compound consisting of three carbon atoms and two nitrogen atoms. In this compound, the pyrazole ring is attached to the same carbon atom as the phenyl group.
Building block in organic synthesis
1-phenyl-2-(1H-pyrazol-1-yl)Ethanone is used as a starting material or intermediate in the synthesis of more complex organic compounds, making it a valuable component in organic chemistry.
Pharmaceutical research
The compound has potential applications in the development of new drugs and biologically active compounds, making it an important subject of study in pharmaceutical research.
Unique chemical properties
The presence of both the phenyl and pyrazole groups in the structure of 1-phenyl-2-(1H-pyrazol-1-yl)Ethanone gives it unique chemical properties, which can be exploited in the synthesis of various organic compounds.
Valuable intermediate
Due to its unique chemical properties and potential applications, 1-phenyl-2-(1H-pyrazol-1-yl)Ethanone is considered a valuable intermediate for the synthesis of a wide range of organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1457-48-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,5 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1457-48:
(6*1)+(5*4)+(4*5)+(3*7)+(2*4)+(1*8)=83
83 % 10 = 3
So 1457-48-3 is a valid CAS Registry Number.
1457-48-3Relevant articles and documents
Preliminary structure-activity relationship (SAR) of a novel series of pyrazole SKF-96365 analogues as potential store-operated calcium entry (SOCE) inhibitors
Dago, Camille D.,Le Maux, Paul,Roisnel, Thierry,Brigaudeau, Christophe,Bekro, Yves-Alain,Mignen, Olivier,Bazureau, Jean-Pierre
, (2018)
From a series of (1R, 1S)-1[β-(phenylalkoxy)-(phenetyl)]-1H-pyrazolium hydrochloride as new analogues of SKF-96365, one has an interesting effect for endoplasmic reticulum (ER) Ca2+ release and store-operated Ca2+ entry (SOCE) (ICsu
α-N-Heteroarylation and α-Azidation of Ketones via Enolonium Species
More, Atul A.,Pathe, Gulab K.,Parida, Keshaba N.,Maksymenko, Shimon,Lipisa, Yuriy B.,Szpilman, Alex M.
, p. 2442 - 2447 (2018/02/23)
Enolonium species, resulting from the umpolung of ketone enolates by Koser's hypervalent iodine reagents activated by boron trifluoride, react with a variety of nitrogen heterocycles to form α-aminated ketones. The reactions are mild and complete in 4-5 h. Additionally, α-azidation of the enolonium species takes place using trimethylsilyl azide as a convenient source of azide nucleophile.
