145701-63-9Relevant academic research and scientific papers
Reaction of a Serine-derived Organozinc Reagent with Chloroformates and Ethyl Oxalyl Chloride Under Palladium Catalysis. Preparation of Protected (2S,6S)-4-Oxo-2,6-diaminopimelic Acid and (2S)-4-Oxoglutamic Acid
Jackson, Richard F. W.,Wishart, Neil,Wythes, Martin J.
, p. 1587 - 1589 (2007/10/02)
Organozinc reagent 1 reacts with phenyl chloroformate under palladium catalysis to give the protected 4-oxo-2,6-diaminopimelic acid derivative 3, derived by formal displacement of both chloride and phenoxide; the symmetrical ketone 3, together with protec
