145790-51-8

Basic information

• Product Name: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID
• Synonyms: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID
• CAS NO: 145790-51-8
• Molecular Formula: C₂₄H₃₃NO₅Si
• Molecular Weight: 443.60802
• Mol File: 145790-51-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 534 °C at 760 mmHg
• Flash Point: 276.7 °C
• Appearance: /
• Density: 1.12 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID(145790-51-8)
• EPA Substance Registry System: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID(145790-51-8)

Safety Data

• Hazardous Substances Data: 145790-51-8(Hazardous Substances Data)

Usage

General Description

(S)-2-(tert-Butoxycarbonylamino)-3-(tert-butyldiphenylsilyloxy)propanoic acid, also known as Boc-Asp(OtBu)-OH, is a chemical compound commonly used in peptide synthesis. It is a derivative of aspartic acid and is often used as a building block for the synthesis of peptides and proteins. The tert-butoxycarbonyl (Boc) protecting group is commonly utilized to protect the amino group of aspartic acid during peptide synthesis, and the diphenylsilyloxy group is often used to protect the hydroxyl group. (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(TERT-BUTYLDIPHENYLSILYLOXY)PROPANOIC ACID is important in the field of medicinal chemistry and drug development, as it is used to create new peptide-based drugs and study the structure-activity relationships of peptide molecules in biological systems.

Upstream product

• 145790-48-3 N-tert-Butoxycarbonyl-O-(tert-butyldiphenylsilyl)-L-serine Benzyl Ester 
• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 59524-02-6 N-tert-butoxycarbonyl-L-serine benzyl ester 

Downstream Products

• 702702-09-8 (2S)-2-(N-tert-butyloxycarbonyl)-amino-1-tert-butyldiphenylsilyloxy-4-diazo-heptan-3-one 
• 873065-74-8 C₂₉H₄₁NO₆Si 
• 873065-67-9 C₂₉H₃₉NO₆Si 
• 1430098-18-2 C₄₉H₅₈N₄O₉Si 
• 1430098-17-1 C₄₀H₄₈N₂O₆Si 
• 702702-13-4 (2S,3S,4R)-N-(tert-butyloxycarbonyl)-2-(tert-butyldiphenylsilyloxymethyl)-4-propyl-azetidin-3-ol 
• 702702-10-1 (2S,4R)-N-(tert-butyloxycarbonyl)-2-(tert-butyldiphenylsilyloxymethyl)-4-propyl-azetidin-3-one 
• 702702-14-5 (2S,3S,4R)-N-(tert-butyloxycarbonyl)-2-hydroxymethyl-4-propyl-azetidin-3-ol 
• 867326-60-1 [1-(tert-butyl-diphenyl-silanyloxymethyl)-2-(dimethyl-phenyl-silanyl)-allyl]-carbamic acid tert-butyl ester 
• 867326-59-8 [1-(tert-butyl-diphenyl-silanyloxymethyl)-2-(dimethyl-phenyl-silanyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

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